In this lecture, Michael McKubre outlines the principles and challenges of electrochemical loading in palladium-deuterium systems, based on decades of work at SRI International. He explains how precise control of surface conditions, current density, and material purity is essential to achieve the high deuterium loading required for the Fleischmann-Pons heat effect. McKubre emphasizes that loading and surface reconstruction are dynamic, time-dependent processes, and that maintaining lattice integrity is critical to avoid cracking and deloading. He concludes that electrochemical loading remains the most effective way to reach the high chemical potentials and absorption fluxes needed for LENR, arguing for both the complexity and promise of the approach. “Electrochemical loading is superior in its ability to create high chemical potential with minimal apparatus and to simultaneously permit high absorption flux.” (30:28)